Systemic Sclerosis 2011

Systemic Sclerosis 2011

1Division of Immunology and Rheumatology, Stanford University School of Medicine and Palo Alto VA Health Care System, 3801 Miranda Avenue, Palo Alto, CA 94305, USA 2Department of Rheumatology, University Hospital Zurich, Gloria street 25, 8091 Zurich, Switzerland 3Division of Rheumatology, Johns Hopkins University, 5501 Hopkins Bayview Circle, Room 1B.7, Baltimore, MD 21224, USA 4Division of Im...

High frequency skin ultrasonography in systemic sclerosis

Background: Systemic sclerosis is an autoimmune connective tissue disorder which is characterised by cutaneous and internal organ fibrosis. Raynaud’s phenomenon is the earliest feature and may precede the onset of the disease by months to years. The heart, lungs, gastrointestinal tract, kidneys and other organs may be involved. Our aim was to evaluate skin thickness and echogenicity in systemic...

Systemic Sclerosis –

Systemic sclerosis.

Regressive systemic sclerosis.

Systemic sclerosis is a disease which usually progresses or reaches a plateau with persistence of symptoms and signs. Regression is extremely unusual. Four cases of established scleroderma are described in which regression is well documented. The significance of this observation and possible mechanisms of disease regression are discussed.